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CD10, Biotin, clone: eBioCB-CALLA (CB-CALLA), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0106-80

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15259439

  • £43.65 / 25µg


Estimated Shipment date
from Supplier 30-07-2018
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Description

Description

Description: The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.Applications Reported: This eBioCB-CALLA (CB-CALLA) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioCB-CALLA (CB-CALLA) antibody has been tested by flow cytometric analysis of normal normal human peripheral blood cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD10
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P08473
CALLA, CD10, NEP, SFE, atriopeptidase, common acute lymphocytic leukemia antigen, enkephalinase, membrane metallo-endopeptidase neutral endopeptidase, enkephalinase, membrane metallo-endopeptidase neutral endopeptidase, enkephalinase, CALLA, CD10, membrane metallo-endopeptidase
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
eBioCB-CALLA (CB-CALLA)
Biotin
MME
Conjugated
MME
IgG2b, kappa
25μg
Store at 2-8°C. Do not freeze.
Primary
4311
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