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CD10 Mouse anti-Human, Alexa Fluor 700, Clone: CB-CALLA, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 56-0106-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15520337

  • £78.88 / 25 tests


Estimated Shipment date
from Supplier 03-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.
Description & Specifications

Specifications

CD10
eBioCB-CALLA (CB-CALLA)
Alexa Fluor 700
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
Conjugated
Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
IgG2b
RUO
Primary
Human