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CCL3 (MIP-1 alpha) Rat anti-Mouse, PerCP-eFluor 710, Clone: DNT3CC, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-7532-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15559366

  • £81.63 / 25µg


EU Stock 2
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Disclaimers:

For Research Use Only.


Specifications

Description

This DNT3CC monoclonal antibody reacts with mouse CCL3. CCL3, also known as MIP-1 alpha (Macrophage Inflammatory Protein 1 alpha), is a member of the CC- subfamily of chemokines and is most closely related to CCL4, or MIP-1 beta. These proteins play critical roles in the recruitment of leukocytes to the site of inflammation. While both CCL3 and CCL4 will attract monocytes, macrophages, and dendritic cells, CCL3 preferentially attracts CD8+ T cells, while CD4+ T cells are more responsive to CCL4. In addition to its chemotactic functions, CCL3 induces inflammatory cytokine secretion, mast cell degranulation, and NK cell activation. It has also been reported to inhibit hematopoetic stem cell proliferation and may be responsible for the maintenance of these cells in a quiescent state. CCL3 signaling is mediated by the G protein-coupled receptors CCR1, CCR4, and CCR5, which are shared with CCL4 and CCL5 (RANTES).
Description & Specifications

Specifications

CCL3 (MIP-1 alpha)
DNT3CC
PerCP-eFluor 710
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
Flow Cytometry (Intracellular Staining)
0.2mg/mL
Conjugated
C-C Motif Chemokine 3, Macrophage Inflammatory Protein 1-alpha
IgG2a
RUO
Primary
Murine