β-Catenin Rabbit Polyclonal Antibody, Epredia™

Stain formalin-fixed, paraffin-embedded tissues with Epredia™ Catenin, β, Rabbit Polyclonal Antibody.

Product Code	Brand	Form	Quantity
12663377	Epredia RB-9035-P1	Concentrated	500 μL
12653377	Epredia RB-9035-P0	Concentrated	100 μL
12643377	Epredia RB-9035-P	Concentrated	1 mL
12693377	Epredia RB-9035-R7	Prediluted	7 mL

Description

The catenins (α, Β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. Β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human and Mouse. Others not tested.

Epitope: C-terminal

Immunogen: A synthetic peptide from the C-terminus of the β-catenin protein

Molecular Weight: 92kDa

Positive Control: MCF-7 cells, Breast CA

Cellular Localization: Cytoplasmic and cell membrane

This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation

Specifications

• Antigen: Catenin, beta
• Classification: Polyclonal
• Host Species: Rabbit
• Research Discipline: Transcription Regulation
• Immunogen: A synthetic peptide from the C-terminus of the beta-catenin protein
• Primary or Secondary: Primary

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Target Species: Human
• Isotype: IgG