Caspase 1 Rat anti-Mouse, Clone: 5B10, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9832-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15278187

Quantity Price
1 £ 121.67 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Regulatory Status RUO
Isotype IgG2a
Host Species Rat
Antigen Caspase 1
Primary or Secondary Primary
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C.
Gene Alias Caspase1
Clone 5B10
Species Reactivity Mouse
Quantity 100μg
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Western Blotting

The monoclonal antibody 5B10 recognizes mouse Caspase-1, a member of the cysteine-requiring aspartate protease family, which plays a critical role in cell suicide known as apoptosis. In particular, it converts pro-IL-1β to mature IL-1β; hence it is also called ICE (interleukin-1β converting enzyme). Upon activation Caspase-1 exists as a tetramer of two p20 and two p10 subunits. There are several isoforms of Caspase-1.

The 5B10 antibody recognizes both the pro-form of about 42kDa and the active p20 form.