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c-Met (HGF Receptor) Rat anti-Mouse, Clone: eBioclone 7, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-8854-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15298097

  • £158.36 / 100µg


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For Research Use Only.


Specifications

Description

The eBioclone 7 monoclonal antibody was generated against a mouse c-Met-Ig fusion protein, and reacts with mouse c-Met-transfected cells. Mouse c-Met (HGFR) is a 170kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.
Description & Specifications

Specifications

c-Met (HGF Receptor)
eBioclone 7
Unlabeled
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Flow Cytometry
0.5mg/mL
aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
hepatocyte growth factor receptor
IgG1
RUO
Primary
Murine