c-Met (HGF Receptor) Rat anti-Mouse, Clone: eBioclone 7, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-8854-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298097

Quantity Price
1 £ 158.36 / 100µg
Estimated Shipment date
from Supplier 05-04-2017
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Description and Specification

Specification

Conjugate Unlabeled
Isotype IgG1
Species Reactivity Mouse
Quantity 100μg
Clone eBioclone 7
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Applications Flow Cytometry
Regulatory Status RUO
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, contains carrier protein/stabilizer if necessary
Format Purified
Gene Alias hepatocyte growth factor receptor
Storage Requirements Store at 2-8°C.
Concentration 0.5mg/mL
Antigen c-Met (HGF Receptor)

The eBioclone 7 monoclonal antibody was generated against a mouse c-Met-Ig fusion protein, and reacts with mouse c-Met-transfected cells. Mouse c-Met (HGFR) is a 170kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.