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c-Met, FITC, clone: eBioclone 97, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-8858-42

Code : Z2

Additional Details : Weight : 0.10000kg

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Product Code. 15310592

  • £186.30 / 100 tests


Estimated Shipment
29-01-2018
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Disclaimers:

For Research Use Only.


Description

Description

Description: The eBioclone 97 monoclonal antibody was generated against a human c-Met-Ig fusion protein, and reacts with human c-Met (HGFR)-transfected cells. Human c-Met is a 145kDa receptor tyrosine kinase (RTK) expressed by epithelial cells of the brain, kidney, liver and other tissues. Binding of its ligand, Hepatocyte Growth Factor (HGF), triggers receptor autophosphorylation, and activation of several downstream effectors including the mitogen-activated protein kinases ERK-1 and ERK-2, and PLC gamma;. Activation of the c-Met signal transduction pathway leads to mulitple cellular responses including cell motility, scattering, proliferation, survival and angiogenesis. Mutations in human c-Met have been implicated in the development of several malignancies.Applications Reported: This eBioclone 97 antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioclone 97 antibody has been pre-titrated and tested by flow cytometric analysis of A549 cells. This can be used at 5 μL (1 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

c-Met (HGF Receptor)
eBioclone 97
FITC
Conjugated
Rat
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (1.0μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HGFR, hepatocyte growth factor receptor
IgG1
RUO
Primary
Human
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