c-Maf Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9855-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15529446

Quantity Price
1 £ 94.28 / 25 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Species Reactivity Human, Mouse
Concentration 5μL (0.0075μg)/test
Quantity 25 tests
Monoclonal or Polyclonal Monoclonal
Gene Alias Maf
Clone sym0F1
Format Conjugated
Isotype IgG2b
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry (Intracellular Staining)
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Regulatory Status RUO
Antigen c-Maf
Conjugate PerCP-eFluor 710
Primary or Secondary Primary
Host Species Mouse

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.