c-Maf Mouse anti-Human, Mouse, PerCP-eFluor 710, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9855-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15539446

Quantity Price
1 £ 239.82 / 100 tests
EU Stock 6
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Description and Specification

Specification

Antigen c-Maf
Isotype IgG2b
Species Reactivity Human, Mouse
Concentration 5μL (0.0075μg)/test
Monoclonal or Polyclonal Monoclonal
Applications Flow Cytometry (Intracellular Staining)
Primary or Secondary Primary
Quantity 100 tests
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Host Species Mouse
Conjugate PerCP-eFluor 710
Gene Alias Maf
Regulatory Status RUO
Clone sym0F1
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.