c-Maf Mouse anti-Human, Mouse, PE, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-9855-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15587246

Quantity Price
1 £ 201.16 / 100 tests
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Isotype IgG2b
Gene Alias Maf
Conjugate PE
Applications Flow Cytometry (Intracellular Staining)
Primary or Secondary Primary
Quantity 100 tests
Species Reactivity Human, Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen c-Maf
Regulatory Status RUO
Format Conjugated
Clone sym0F1
Host Species Mouse

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.

Sym0F1 does not cross-react with MafA or MafB.