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c-Maf Mouse anti-Human, Mouse, PE, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9855-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15587246

  • £201.16 / 100 tests


EU Stock 3
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Disclaimers:

For Research Use Only.


Specifications

Description

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.

Sym0F1 does not cross-react with MafA or MafB.
Description & Specifications

Specifications

c-Maf
sym0F1
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.06μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Maf
IgG2b
RUO
Primary
Murine