c-Maf Mouse anti-Human, Mouse, eFluor 660, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9855-80

25UG Anti-Human/Mouse c-Maf eFluor 660

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15560147

Quantity Price
1 £ 129.5 / 25µg
Estimated Shipment date
from Supplier 22-02-2017
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Description and Specification

Specification

Antigen c-Maf
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry (Intracellular Staining)
Isotype IgG2b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal or Polyclonal Monoclonal
Clone sym0F1
Format Conjugated
Gene Alias Maf
Host Species Mouse
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human, Mouse
Primary or Secondary Primary
Concentration 0.2mg/mL
Conjugate eFluor 660

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.