c-Maf Mouse anti-Human, Mouse, eFluor 660, Clone: sym0F1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-9855-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15560147

Quantity Price
1 £ 84.99 / 25µg
EU Stock 1
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Description and Specification

Specification

Isotype IgG2b
Monoclonal or Polyclonal Monoclonal
Clone sym0F1
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen c-Maf
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry (Intracellular Staining)
Host Species Mouse
Species Reactivity Human, Mouse
Gene Alias Maf
Concentration 0.2mg/mL
Conjugate eFluor 660
Regulatory Status RUO
Primary or Secondary Primary
Quantity 25μg
Format Conjugated

The sym0F1 monoclonal antibody reacts with human and mouse c-Maf, a 42kDa basic leucine zipper transcription factor shown to be involved in the neural, ocular and hematopoietic systems. In hematopoietic cells, it was first shown to be crucial for IL-4 expression in Th2 and was the first transcription factor believed to be Th subset-specific. More recent evidence shows that specific phospho-tyrosine residues lead to upregulation of IL-4. c-Maf has also been shown to be important to differentiation and function in both Th17 and Tfh cells. It drives expression of IL-21 in both cell types, while promoting expression of IL-23R in Th17 and CXCR5 in Tfh as well.