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BX 513 hydrochloride, Tocris Bioscience™

Selective CCR1 antagonist

Brand:  Tocris (Bio-Techne) 276910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13460554

  • £183.48 / 10mg


Estimated Shipment
29-11-2018
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Description

Description

Selective CCR1 receptor antagonist (Ki values are 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors respectively). Inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Also a full inverse agonist at US28, a? HCMV-encoded chemokine receptor.
Specifications

Chemical Identifiers

1216540-18-9
481.461
bx 513 hydrochloride, bx-513 hydrochloride, 1-piperidinepentanenitrile,4-4-chlorophenyl-4-hydroxy-a,a-diphenyl-,hydrochloride, 4-4-chlorophenyl-4-hydroxy-?,?-diphenyl-1-piperidinepentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile-hydrogen chloride 1/1
5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile;hydrochloride
C28H30Cl2N2O
SSZWNUGWOGONQJ-UHFFFAOYSA-N
56972186
C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4.Cl

Specifications

BX 513 hydrochloride
1216540-18-9
bx 513 hydrochloride, bx-513 hydrochloride, 1-piperidinepentanenitrile,4-4-chlorophenyl-4-hydroxy-a,a-diphenyl-,hydrochloride, 4-4-chlorophenyl-4-hydroxy-?,?-diphenyl-1-piperidinepentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile hydrochloride, 5-4-4-chlorophenyl-4-hydroxypiperidin-1-yl-2,2-diphenylpentanenitrile-hydrogen chloride 1/1
C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(C#N)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
481.461
481.46
10mg
C28H30Cl2N2O
SSZWNUGWOGONQJ-UHFFFAOYSA-N
5-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile;hydrochloride
56972186
>99%
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