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bPiDDB, Tocris Bioscience™

Orthosteric nAChR antagonist

Brand:  Tocris (Bio-Techne) 322110

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442594

  • £116.13 / 10mg

Estimated Shipment date
from Supplier 26-11-2019

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Description

Description

Orthosteric neuronal nicotinic acetylcholine receptor (nAChR) antagonist (IC50 values are 0.17, 0.25, 0.4, 4.8, 6.5, 8.2, 20 and 34 μM at α3β4, α1β1εδ, α3β4β3, α6β4β3, α7, α4β2, α3β2β3 and α6/3β2β3 receptors respectively). Attenuates nicotine-evoked dopamine release from the ventral tegmental area in vivo (IC50 = 0.2 nM) and reduces nicotine self-administration in rats. Brain penetrant.
Specifications

Chemical Identifiers

525596-66-1
514.39
bpiddb, chembl54331, n,n'-dodecylbis-picolinium bromide, n,n'-dodecane-1,12-diyl-bis-3-picolinium dibromide, 1,1'-1,12-dodecanediyl bis 3-methylpyridinium dibromide
3-methyl-1-[12-(3-methylpyridin-1-ium-1-yl)dodecyl]pyridin-1-ium;dibromide
C24H38Br2N2
NNPBJCAIRCFEFZ-UHFFFAOYSA-L
9983961
CC1=C[N+](=CC=C1)CCCCCCCCCCCC[N+]2=CC=CC(=C2)C.[Br-].[Br-]

Specifications

10mg
525596-66-1
bpiddb, chembl54331, n,n'-dodecylbis-picolinium bromide, n,n'-dodecane-1,12-diyl-bis-3-picolinium dibromide, 1,1'-1,12-dodecanediyl bis 3-methylpyridinium dibromide
CC1=C[N+](=CC=C1)CCCCCCCCCCCC[N+]2=CC=CC(=C2)C.[Br-].[Br-]
514.39
514.38
bPiDDB
C24H38Br2N2
NNPBJCAIRCFEFZ-UHFFFAOYSA-L
3-methyl-1-[12-(3-methylpyridin-1-ium-1-yl)dodecyl]pyridin-1-ium;dibromide
9983961
>98%
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