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BMS CCR2 22, Tocris Bioscience™

High affinity, potent CCR2 antagonist

Brand:  RD Systems (Bio-Techne) 31291

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 1mg

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Product Code. 13462484

  • £120.15 / 1mg


Estimated Shipment
31-10-2018
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Description

Description

High affinity CCR2 chemokine receptor antagonist (IC50 = 5.1 nM). Displays potent functional antagonism, IC50 values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.
Specifications

Chemical Identifiers

445479-97-0
593.666
2-isopropylaminocarbonyl amino-n-2-cis-2-4-methylthio benzoyl amino cyclohexyl amino-2-oxoethyl-5-trifluoromethyl benzamide, 2-3-isopropylureido-n-2-cis-2-4-methylthio benzamido cyclohexyl amino-2-oxoethyl-5-trifluoromethyl benzamide, n-2-1r,2s-2-4-methylsulfanyl benzamido cyclohexyl amino-2-oxoethyl-2-propan-2-yl carbamoyl amino-5-trifluoromethyl benzamide
N-[2-[[(1R,2S)-2-[(4-methylsulfanylbenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamide
C28H34F3N5O4S
IBPXYDUJQWENPM-PKTZIBPZSA-N
57350027
CC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SC

Specifications

BMS CCR2 22
445479-97-0
2-isopropylaminocarbonyl amino-n-2-cis-2-4-methylthio benzoyl amino cyclohexyl amino-2-oxoethyl-5-trifluoromethyl benzamide, 2-3-isopropylureido-n-2-cis-2-4-methylthio benzamido cyclohexyl amino-2-oxoethyl-5-trifluoromethyl benzamide, n-2-1r,2s-2-4-methylsulfanyl benzamido cyclohexyl amino-2-oxoethyl-2-propan-2-yl carbamoyl amino-5-trifluoromethyl benzamide
CC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SC
593.666
593.66
1mg
C28H34F3N5O4S
IBPXYDUJQWENPM-PKTZIBPZSA-N
N-[2-[[(1R,2S)-2-[(4-methylsulfanylbenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamide
57350027
>98%
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