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BMS CCR2 22, Tocris Bioscience™

High affinity, potent CCR2 antagonist

Brand:  RD Systems (Bio-Techne) 31291

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 1mg

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Product Code. 13462484

  • £120.15 / 1mg


Estimated Shipment
31-08-2018
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Description

Description

High affinity CCR2 chemokine receptor antagonist (IC50 = 5.1 nM). Displays potent functional antagonism, IC50 values are 1 and 18 nM for chemotaxis and antagonism of calcium flux respectively. Selective over CCR3.
Specifications

Chemical Identifiers

445479-97-0
593.666
2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
C28H34F3N5O4S
IBPXYDUJQWENPM-PKTZIBPZSA-N
57350027

Specifications

BMS CCR2 22
445479-97-0
C28H34F3N5O4S
IBPXYDUJQWENPM-PKTZIBPZSA-N
N-[2-[[(1R,2S)-2-[(4-methylsulfanylbenzoyl)amino]cyclohexyl]amino]-2-oxoethyl]-2-(propan-2-ylcarbamoylamino)-5-(trifluoromethyl)benzamide
57350027
1mg
>98%
2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
CC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SC
593.666
593.66
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