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BMS 193885, Tocris Bioscience™

Potent, competitive NPY Y1 receptor antagonist

Brand:  Tocris (Bio-Techne) 324210

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13462634

  • £217.80 / 10mg


Estimated Shipment
31-10-2018
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Description

Description

Potent, competitive neuropeptide (NPY) Y1 antagonist (Ki = 3.3 nM, IC50 = 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. Reduces food intake and body weight via central Y1 inhibition and is brain penetrant.
Specifications

Chemical Identifiers

679839-66-8
680.799
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;(2S)-2-hydroxypropanoic acid
C36H48N4O9
BYHJIPSVXAFCDI-WNQIDUERSA-N
56972234
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)NC(=O)NCCCN3CCC(CC3)C4=CC(=CC=C4)OC)C(=O)OC.CC(C(=O)O)O

Specifications

BMS 193885
679839-66-8
1,4-dihydro-4-3-3-4-3-methoxyphenyl-1-piperidinyl propyl amino carbonyl amino phenyl-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3,5-dimethyl ester l-lactate
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)NC(=O)NCCCN3CCC(CC3)C4=CC(=CC=C4)OC)C(=O)OC.CC(C(=O)O)O
680.799
680.79
10mg
C36H48N4O9
BYHJIPSVXAFCDI-WNQIDUERSA-N
dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;(2S)-2-hydroxypropanoic acid
56972234
>99%
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