Blood Group Antigen H (O) Type 1, clone: 17-206, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9810-82
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: The monoclonal antibody 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells. The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells. The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases. Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen). Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined. The 17-206 antibody does not recognize blood group antigen H (O) type 2.Applications Reported: This 17-206 antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections and ELISA.Applications Tested: This 17-206 antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using either high or low pH antigen retrieval at less than or equal to 5 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|Blood Group H1 (O) Type 1|
|PBS with 0.09% sodium azide; pH 7.2|
|ABH, BG-H1, BG-H, Blood Group H ab antigen|
|Store at 2-8°C.|
For Research Use Only.