Blood Group H1 (O) Type 1 Mouse anti-Human, Clone: 17-206, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9810-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298177

Quantity Price
1 £ 136.24 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
Add to basket


Description and Specification

Specification

Primary or Secondary Primary
Format Purified
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Quantity 100μg
Regulatory Status RUO
Antigen Blood Group H1 (O) Type 1
Isotype IgG3
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Applications Enzyme Linked Immunosorbent Assay
Applications Immunohistochemistry (Formalin/Paraffin)
Species Reactivity Human
Clone 17-206

The monoclonal antibody 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells. The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells. The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases. Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen). Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined. The 17-206 antibody does not recognize blood group antigen H (O) type 2.