Blood Group H1 (O) Mouse anti-Human, Alexa Fluor 488, Clone: 17-206, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9810-80

25UG ANTI-HU BLOOD GROUP AG H(O) TYPE1 AF 488

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15382080

Quantity Price
1 £ 113.0 / 25µg
Estimated Shipment date
from Supplier 12-12-2016
Add to basket


Description and Specification

Specification

Antigen Blood Group H1 (O)
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Immunohistochemistry (Frozen)
Clone 17-206
Concentration 0.5mg/mL
Conjugate Alexa Fluor 488
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Isotype IgG3
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells. The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells. The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases. Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen). Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined. The 17-206 antibody does not recognize blood group antigen H (O) type 2.