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BIIE 0246, Tocris Bioscience™

Potent, selective non-peptide NPY Y2 receptor antagonist

Brand:  Tocris (Bio-Techne) 1700/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13438663

  • £291.73 / 10mg

Estimated Shipment
28-06-2019

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Description

Description

Potent, selective and competitive non-peptide antagonist for the neuropeptide Y Y2 receptor (IC50 = 15 nM). Displays > 650-fold selectivity over Y1, Y4 and Y5 receptors. Active in vivo.
Specifications

Chemical Identifiers

246146-55-4
896.066
d06gfz, cyclopentaneacetamide, n-1s-4-aminoiminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl, 2s-5-diaminomethylideneamino-n-2-3,5-dioxo-1,2-di phenyl-1,2,4-triazolidin-4-yl ethyl-2-2-1-2-oxo-2-4-6-oxo-5,11-dihydrobenzo c 2 benzazepin-11-yl piperazin-1-yl ethyl cyclopentyl acetyl amino pentanamide, 2s-5-carbamimidamido-n-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl-2-2-1-2-oxo-2-4-10-oxo-9-azatricyclo 9.4.0.0 3 ,? pentadeca-1 15 ,3,5,7,11,13-hexaen-2-yl piperazin-1-yl ethyl cyclopentyl acetamido pentanamide, n-1s-4-amino-iminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl-amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl-cyclopentaneacetamide, n-1s-4-aminoiminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl-cyclopentaneacetamide
(2S)-5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide
C49H57N11O6
RSJAXPUYVJKAAA-JPGJPTAESA-N
9811493
C1CCC(C1)(CC(=O)NC(CCCN=C(N)N)C(=O)NCCN2C(=O)N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)CC(=O)N5CCN(CC5)C6C7=CC=CC=C7C(=O)NC8=CC=CC=C68

Specifications

BIIE 0246
246146-55-4
d06gfz, cyclopentaneacetamide, n-1s-4-aminoiminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl, 2s-5-diaminomethylideneamino-n-2-3,5-dioxo-1,2-di phenyl-1,2,4-triazolidin-4-yl ethyl-2-2-1-2-oxo-2-4-6-oxo-5,11-dihydrobenzo c 2 benzazepin-11-yl piperazin-1-yl ethyl cyclopentyl acetyl amino pentanamide, 2s-5-carbamimidamido-n-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl-2-2-1-2-oxo-2-4-10-oxo-9-azatricyclo 9.4.0.0 3 ,? pentadeca-1 15 ,3,5,7,11,13-hexaen-2-yl piperazin-1-yl ethyl cyclopentyl acetamido pentanamide, n-1s-4-amino-iminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl-amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl-cyclopentaneacetamide, n-1s-4-aminoiminomethyl amino-1-2-3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl ethyl amino carbonyl butyl-1-2-4-6,11-dihydro-6-oxo-5h-dibenz b,e azepin-11-yl-1-piperazinyl-2-oxoethyl-cyclopentaneacetamide
C1CCC(C1)(CC(=O)NC(CCCN=C(N)N)C(=O)NCCN2C(=O)N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)CC(=O)N5CCN(CC5)C6C7=CC=CC=C7C(=O)NC8=CC=CC=C68
896.066
896.06
10mg
C49H57N11O6
RSJAXPUYVJKAAA-JPGJPTAESA-N
(2S)-5-(diaminomethylideneamino)-N-[2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]-2-[[2-[1-[2-oxo-2-[4-(6-oxo-5,11-dihydrobenzo[c][1]benzazepin-11-yl)piperazin-1-yl]ethyl]cyclopentyl]acetyl]amino]pentanamide
9811493
>98%
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