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BAY 41-2272, Tocris Bioscience™

Soluble guanylyl cyclase (sGC) activator

Brand:  RD Systems (Bio-Techne) 4430/50

Code : Z1

Additional Details : Weight : 0.00050kg

Quantity 50mg

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Product Code. 13434744

  • £809.97 / 50mg

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Description

Description

Activator of soluble guanylyl cyclase (sGC); acts at a nitric oxide (NO)-independent regulatory site in the sGC α1 subunit. Inhibits platelet aggregation (IC50 = 36 nM) and phenylephrine-induced contractions of rabbit aorta (IC50 = 0.30 μM). Also reduces vascular smooth muscle growth through cAMP- and cGMP-dependent PKA and PKG pathways.
Specifications

Chemical Identifiers

256376-24-6
360.396
unii-34a162j6wb, 3-4-amino-5-cyclopropylpyrimidin-2-yl-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridine, 5-cyclopropyl-2-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-ylamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl-4-pyrimidinamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine, 5-cyclopropyl-2-1-2-fluorophenyl methyl pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine, d0o9cz, 4-pyrimidinamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl, bay hplc, 5-cyclopropyl-2-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine
5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
C20H17FN6
ATOAHNRJAXSBOR-UHFFFAOYSA-N
9798973
C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F

Specifications

50mg
256376-24-6
unii-34a162j6wb, 3-4-amino-5-cyclopropylpyrimidin-2-yl-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridine, 5-cyclopropyl-2-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-ylamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl-4-pyrimidinamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine, 5-cyclopropyl-2-1-2-fluorophenyl methyl pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine, d0o9cz, 4-pyrimidinamine, 5-cyclopropyl-2-1-2-fluorophenyl methyl-1h-pyrazolo 3,4-b pyridin-3-yl, bay hplc, 5-cyclopropyl-2-1-2-fluorobenzyl-1h-pyrazolo 3,4-b pyridin-3-yl pyrimidin-4-amine
C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F
360.396
360.39
BAY 41-2272
C20H17FN6
ATOAHNRJAXSBOR-UHFFFAOYSA-N
5-cyclopropyl-2-[1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-4-amine
9798973
>98%
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