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Tocris Bioscience™ BAN ORL 24

Potent and selective NOP antagonist

POA

Specifications

Product Type BAN ORL 24
Inhibitors BAN ORL 24
Molecular Weight 506.51
Purity >97
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Description

Description

Potent and selective NOP receptor antagonist (IC50 values are 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively). Inhibits nociceptin-induced stimulation of [35S]-GTPγS binding and Ca2+ mobilization in CHO cells in vitro and antagonizes NOP agonist-induced reduction in locomotor activity in vivo. Brain penetrant.
Specifications

Specifications

BAN ORL 24
BAN ORL 24
506.51
>97

For Research Use Only