B7-H4 Mouse anti-Human, PE, Clone: H74, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-5949-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15597056

Quantity Price
1 £ 195.05 / 100 tests
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Conjugate PE
Isotype IgG1
Concentration 5μL (0.125μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Applications Flow Cytometry
Clone H74
Quantity 100 tests
Species Reactivity Human
Host Species Mouse
Antigen B7-H4
Gene Alias B7H4, B7S1, B7-S1, B7X
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary

The H74 monoclonal antibody was generated and reacts with human B7-S1, also known as B7-H4 and B7x. Cross reactivity of this antibody to other proteins has not been determined. B7S1 is a newly discovered member of the B7 family. It is speculated that the costimulatory regulation of T cells by B7S1 is influenced by the activation status of B cells. While it is reported that BTLA is a counter receptor for B7S1, further studies are needed to definitely determine the B7-H4 ligand. H74 stains human B7-H4 transfected cells and not peripheral blood cells. Exact expression pattern of B7-H4 has not been fully characterized.