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AZD 5438, Tocris Bioscience™

Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9

Brand:  Tocris (Bio-Techne) 396850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13443904

  • £739.41 / 50mg

Estimated Shipment date
from Supplier 20-12-2019

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Description

Description

Potent inhibitor of cyclin dependent kinases (cdks; reported IC50 values are 6 - 45, 14, 16 and 20 nM for cdk2, cdk5, cdk1 and cdk9 respectively). Also inhibits cdk4 and cdk7 in the sub micromolar range. Exhibits antiproliferative activity in human tumor cell lines. Blocks cell cycling at G2-M, S and G1 phases; reduces the proportion of actively cycling cells in vivo.
Specifications

Chemical Identifiers

602306-29-6
371.459
4-1-isopropyl-2-methyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl pyrimidin-2-amine, 2-pyrimidinamine,4-2-methyl-1-1-methylethyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl, 4-2-methyl-1-isopropyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl-2-pyrimidinamine, 4-2-methyl-3-propan-2-ylimidazol-4-yl-n-4-methylsulfonylphenyl pyrimidin-2-amine, 4-3-isopropyl-2-methylimidazol-4-yl-n-4-methanesulfonylphenyl pyrimidin-2-amine, pubchem19336, d06why, 4-2-methyl-1-1-methylethyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl-2-pyrimidinamine, 4-1-isopropyl-2-methylimidazol-5-yl-2-4-mesylanilino pyrimidine
4-(2-methyl-3-propan-2-ylimidazol-4-yl)-N-(4-methylsulfonylphenyl)pyrimidin-2-amine
C18H21N5O2S
WJRRGYBTGDJBFX-UHFFFAOYSA-N
16747683
CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C

Specifications

50mg
602306-29-6
4-1-isopropyl-2-methyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl pyrimidin-2-amine, 2-pyrimidinamine,4-2-methyl-1-1-methylethyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl, 4-2-methyl-1-isopropyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl-2-pyrimidinamine, 4-2-methyl-3-propan-2-ylimidazol-4-yl-n-4-methylsulfonylphenyl pyrimidin-2-amine, 4-3-isopropyl-2-methylimidazol-4-yl-n-4-methanesulfonylphenyl pyrimidin-2-amine, pubchem19336, d06why, 4-2-methyl-1-1-methylethyl-1h-imidazol-5-yl-n-4-methylsulfonyl phenyl-2-pyrimidinamine, 4-1-isopropyl-2-methylimidazol-5-yl-2-4-mesylanilino pyrimidine
CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C
371.459
371.46
AZD 5438
C18H21N5O2S
WJRRGYBTGDJBFX-UHFFFAOYSA-N
4-(2-methyl-3-propan-2-ylimidazol-4-yl)-N-(4-methylsulfonylphenyl)pyrimidin-2-amine
16747683
>99%
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