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AZ 3146, Tocris Bioscience™

Potent and selective Mps1 kinase inhibitor

Brand:  Tocris (Bio-Techne) 399410

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13433944

  • £248.43 / 10mg

Estimated Shipment date
from Supplier 02-04-2020

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Description

Description

Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembly checkpoint. Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.
Specifications

Chemical Identifiers

1124329-14-1
452.559
9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy-phenyl amino-7-methyl-7,9-dihydro-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yloxy phenylamino-7-methyl-7h-purin-8 9h-one, 9-cyclopentyl-7,9-dihydro-2-2-methoxy-4-1-methyl-4-piperidinyl oxy phenyl amino-7-methyl-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methylpurin-8-one, 8h-purin-8-one, 9-cyclopentyl-7,9-dihydro-2-2-methoxy-4-1-methyl-4-piperidinyl oxy phenyl amino-7-methyl, au5, az hplc, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxyanilino-7-methylpurin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methyl-7,9-dihydro-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methyl-7h-purin-8 9h-one
9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one
C24H32N6O3
YUKWVHPTFRQHMF-UHFFFAOYSA-N
56973724
CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC

Specifications

10mg
1124329-14-1
9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy-phenyl amino-7-methyl-7,9-dihydro-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yloxy phenylamino-7-methyl-7h-purin-8 9h-one, 9-cyclopentyl-7,9-dihydro-2-2-methoxy-4-1-methyl-4-piperidinyl oxy phenyl amino-7-methyl-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methylpurin-8-one, 8h-purin-8-one, 9-cyclopentyl-7,9-dihydro-2-2-methoxy-4-1-methyl-4-piperidinyl oxy phenyl amino-7-methyl, au5, az hplc, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxyanilino-7-methylpurin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methyl-7,9-dihydro-8h-purin-8-one, 9-cyclopentyl-2-2-methoxy-4-1-methylpiperidin-4-yl oxy phenyl amino-7-methyl-7h-purin-8 9h-one
CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC
452.559
452.55
AZ 3146
C24H32N6O3
YUKWVHPTFRQHMF-UHFFFAOYSA-N
9-cyclopentyl-2-[2-methoxy-4-(1-methylpiperidin-4-yl)oxyanilino]-7-methylpurin-8-one
56973724
>99%
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