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AZ 11645373, Tocris Bioscience™

Potent and selective human P2X7 antagonist

Brand:  Tocris (Bio-Techne) 331710

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13442774

  • £155.82 / 10mg

Estimated Shipment date
from Supplier 02-04-2020

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Description

Description

Potent and selective human P2X7 antagonist (KB values are 5 - 7 and > 10,000 nM at hP2X7 and rP2X7 respectively) that is completely without effect at all other P2X subtypes. Inhibits BzATP-mediated calcium influx and inhibits ATP-mediated IL-1β release in vitro (KB values are 15 and 92 nM respectively).
Specifications

Chemical Identifiers

227088-94-0
463.508
3-1-3'-nitro 1,1'-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl-2,4-thiazolidinedione, d02efx, 2,4-thiazolidinedione, 3-1-3'-nitro 1,1'-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl, 3-1-4-3-nitrophenyl phenoxy-4-pyridin-4-yl butan-2-yl-1,3-thiazolidine-2,4-dione, 3-1-3'-nitro-1,1'-biphenyl-4-yl oxy-4-pyridin-4-yl butan-2-yl-1,3-thiazolidine-2,4-dione, 3-1-3-nitro 1,1-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl-2,4-thiazolidinedione
3-[1-[4-(3-nitrophenyl)phenoxy]-4-pyridin-4-ylbutan-2-yl]-1,3-thiazolidine-2,4-dione
C24H21N3O5S
VQEHBLGYANQWEA-UHFFFAOYSA-N
9804433
C1C(=O)N(C(=O)S1)C(CCC2=CC=NC=C2)COC3=CC=C(C=C3)C4=CC(=CC=C4)[N+](=O)[O-]

Specifications

10mg
227088-94-0
3-1-3'-nitro 1,1'-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl-2,4-thiazolidinedione, d02efx, 2,4-thiazolidinedione, 3-1-3'-nitro 1,1'-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl, 3-1-4-3-nitrophenyl phenoxy-4-pyridin-4-yl butan-2-yl-1,3-thiazolidine-2,4-dione, 3-1-3'-nitro-1,1'-biphenyl-4-yl oxy-4-pyridin-4-yl butan-2-yl-1,3-thiazolidine-2,4-dione, 3-1-3-nitro 1,1-biphenyl-4-yl oxy methyl-3-4-pyridinyl propyl-2,4-thiazolidinedione
C1C(=O)N(C(=O)S1)C(CCC2=CC=NC=C2)COC3=CC=C(C=C3)C4=CC(=CC=C4)[N+](=O)[O-]
463.508
463.51
AZ 11645373
C24H21N3O5S
VQEHBLGYANQWEA-UHFFFAOYSA-N
3-[1-[4-(3-nitrophenyl)phenoxy]-4-pyridin-4-ylbutan-2-yl]-1,3-thiazolidine-2,4-dione
9804433
>98%
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