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Auranofin, Tocris Bioscience™

Thioredoxin reductase inhibitor; induces MPT

Brand:  RD Systems (Bio-Techne) 4600/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13444974

  • £83.79 / 10mg

Estimated Shipment date
from Supplier 16-12-2019

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Description

Description

Inhibitor of thioredoxin reductase (TrxR) (IC50 = 20 nM; Ki = 4 nM for the NADPH-reduced form of human cytosolic TrxR). Thought to induce the mitochondrial permeability transition via inhibition of mitochondrial TrxR. Also exhibits anti-inflammatory and immunosuppressive activities; inhibits 5-lipoxygenase at high concentrations and stimulates LTA hydrolase at low concentrations.
Specifications

Chemical Identifiers

34031-32-8
678.483
4-2-aminoethyl benzene sulfonyl fluoride hydrochloride
gold(1+);3,4,5-triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolate;triethylphosphane
C20H34AuO9PS
AUJRCFUBUPVWSZ-UHFFFAOYSA-M
24199313
CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+]

Specifications

10mg
34031-32-8
4-2-aminoethyl benzene sulfonyl fluoride hydrochloride
CCP(CC)CC.CC(=O)OCC1C(C(C(C(O1)[S-])OC(=O)C)OC(=O)C)OC(=O)C.[Au+]
678.483
678.48
Auranofin
C20H34AuO9PS
AUJRCFUBUPVWSZ-UHFFFAOYSA-M
gold(1+);3,4,5-triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolate;triethylphosphane
24199313
>98%
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