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Tocris Bioscience™ Asenapine maleate

Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Brand:  Tocris Bioscience™ 373710

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13443524

  • £173.46 / 10mg

Estimated Shipment date
from Supplier 23-10-2019

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Description

Description

Novel psychopharmacologic agent. Displays antagonist activity at 5-HT, dopamine, noradrenalin and histamine receptor subtypes (pKi values are 8.60, 8.40, 10.15, 9.75, 10.46, 8.84, 9.60, 9.94, 8.85, 8.90, 8.84, 9.38, 8.95, 8.93, 8.9, 9.49, 8.91, 9.00 and 8.21 for 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT6, 5-HT7, D1, D2L, D2S, D3, D4, α1A, α2A, α2B, α2C, H1 and H2 receptors respectively). Displays no appreciable affinity for muscarinic receptors. Exhibits potent activity in animal models predictive of antipsychotic efficacy.
Specifications

Specifications

Asenapine maleate
>98
10mg
Asenapine maleate
401.84
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