missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ AS 605240
Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor
POA
Description
Potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8 nM). Displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive.Specifications
>98% |
For Research Use Only