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Tocris Bioscience™ AS 605240

Potent and selective PI 3-kinase γ (PI 3-Kγ) inhibitor

Brand:  Tocris Bioscience™ 357850

Code : Z1

Additional Details : Weight : 0.01000kg

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Product Code. 13433234

  • £646.80 / 50mg

Estimated Shipment date
from Supplier 01-04-2020

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Description

Description

Potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8 nM). Displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. Suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. Orally active and ATP-competitive.
Specifications

Specifications

AS 605240
>98
50mg
AS 605240
257.27
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