Arginase Mouse anti-Human, Alexa Fluor 488, Clone: sl6arg, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9779-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15500307

Quantity Price
1 £ 164.47 / 100µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Isotype IgG1
Antigen Arginase
Applications Immunocytochemistry
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Concentration 0.5mg/mL
Species Reactivity Human
Clone sl6arg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Monoclonal or Polyclonal Monoclonal
Format Conjugated
Quantity 100μg
Conjugate Alexa Fluor 488
Primary or Secondary Primary
Regulatory Status RUO

The monoclonal antibody sl6arg recognizes human Arginase-1, a 35kDa enzyme that that helps eliminate nitrogen by converting L-arginine to urea and L-ornithine which further converts to polyamine. These polyamines are important for cell proliferation and removal of toxins that arise from protein degradation. Expression is found in the liver, neutrophils, as well as myeloid derived suppressor cells (MDSC) and neural stem cells. Expression in macrophages has not been determined in humans, while in mice expression in M2 macrophages is well established. Arginase-1 may be expressed in the myeloid population in breast cancer tumors and is typically found in the majority of hepatocellular carcinomas.