APP (Amyloid Precursor Protein) Mouse anti-Human, Mouse, Rat, Clone: 22C11, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9749-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionApplications Tested: This 22C11 antibody has been tested by immunocytochemistry of methanol-fixed cells and can be used at less than or equal to 2.5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Amyloid Precursor Protein (APP) or Amyloid beta protein functions as a cell surface kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1; APP is rapidly internalized via clathrin-coated pits. APP is important for neurite growth, neuronal adhesion and axonogenesis. Mutations in the APP gene can lead to Alzheimer disease 1 (AD1). This anitbody recognizes APP (b-APP770) with a MW of approximately 100kDa.
|APP (Amyloid Precursor Protein)|
|PBS with 0.09% sodium azide; pH 7.2|
|P08592, P12023, P05067|
|AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2|
|Human, Mouse, Rat|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry|
|11820, 351, 54226|
For Research Use Only.