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VEGF Mouse anti-Human, Unlabeled, Clone: G153-694, BD
Mouse Monoclonal Antibody
Brand: BD Biosciences 555036
Additional Details : Weight : 0.01000kg
Description
Vascular endothelial growth factor (VEGF) is a heparin-binding, dimeric protein related to the PDGF/sis family of growth factors. Major sources of VEGF include pituitary cells, monocytes/macrophages, smooth muscle, and keratinocytes. VEGF is a mitogen for endothelial cells, activates and is chemoattractant for monocytes, enhances blood vessel permeability, and is a pro-coagulant. Human VEGF occurs in several molecular variants arising by alternative splicing of the mRNA. The splice forms of VEGF differ in biological properties. VEGF is a homodimeric heavily glycosylated protein of 46-48kDa (18-25kDa subunits). Glycosylation is not required, however, for biological activity. The subunits are linked by disulphide bonds. Different isoforms of VEGF have different properties in vitro and this may apply also to their in vivo functions.
Immunofluorescence, Immunohistochemistry
Specifications
VEGF | |
Monoclonal | |
0.5mg/mL | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Affinity Purified | |
RUO | |
Primary | |
Store undiluted at 4°C |
Immunohistochemistry | |
G153-694 | |
Unconjugated | |
Mouse | |
0.5 mg | |
Immunology | |
Human | |
IgG2b κ |
For Research Use Only.