anti-Synuclein, α Ab-4; Polyclonal; Millipore™ (Chemicon™)

Brand: Merck Millipore

Manufacturer Part Number: AB5038

Anti-synuclein, A. 50µL

UNSPSC: 12352203

Code: Z1

Additional Details:
Additional Details: Weight: 1.00000kg

Product Code. 12778786

Quantity Price
1 £ 394.54 / 50µL
Estimated Shipment date
from Supplier 06-12-2016
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Description and Specification


Antigen Synuclein, α Ab-4
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Rat
Format Serum
Host Species Rabbit
Immunogen Human α-synuclein residues 111-131 coupled to KLH. The peptide sHuence is N-GILEDMPVDPDNEAYEMPSEEC-C.
Quantity 50μL
Regulatory Status RUO
Research Discipline Neuroscience
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal

α -Synuclein is a small (140-amino acid) cytoplasmic protein of unclear function that is enriched in presynaptic terminals and is the precursor protein of a nonamyloid β component of senile plaques in Alzeheimer's Disease (AD). α -Synuclein is located predominantly in the presynaptic nerve terminals in the brain but is also found in low concentrations in all tissues except liver. Recent studies have shown that abnormal aggregation and accumulation of synaptic proteins, including alpha-Synuclein might be associated with plaque formation in AD and seems to be a major component of Lewy bodies in dementia with Lewy bodies (DLB). It has also been identified in the Glial Cytoplasmic Inclusions (GCIs) found in Multiple System Atrophy (MSA).

Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting