SR-BI Polyclonal Antibody, Invitrogen™

SR-BI Antibody, PA1-16803, from Invitrogen™. Species Reactivity: Hamster, Human, Mink, Mouse, Rat, Rodent; Applications: FACS, ICC, IF, IHC (Paraffin), WB.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-16803

SR-BI

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11585383

Quantity Price
1 £ 333.0 / 100µL
Estimated Shipment date
from Supplier 11-01-2017
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Description and Specification

Specification

Antigen SR-BI
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry (Paraffin)
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Hamster
Cross Reactivity Human
Cross Reactivity Mink
Cross Reactivity Mouse
Cross Reactivity Rat
Cross Reactivity Rodent
Format Purified
Formulation 100μL purified antibody (3mg/mL) in tris citrate and 0.09% sodium azide; pH 7-8
Gene Accession No. P97943, Q61009, Q8WTV0
Gene Alias SCARB1, SR-B1, SR-BI, Scavenger Receptor-BI, Scavenger Receptor-B1
Gene Symbols SCARB1
Host Species Goat
Immunogen Synthetic peptide corresponding to the C-terminal residues 400-509 of mouse SR-BI.
Isotype IgG
Quantity 100μL
Species Reactivity Hamster, Human, Mink, Mouse, Rat, Rodent
Storage Requirements Store at 4° C
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 20778, 25073, 949

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Host Species: Goat
Cross Reactivity: Hamster, Human, Mink, Mouse, Rat, Rodent
Isotype: IgG
Immunogen: Synthetic peptide corresponding to the C-terminal residues 400-509 of mouse SR-BI.
Formulation: 100μL purified antibody (3mg/mL) in tris citrate and 0.09% sodium azide; pH 7-8
Synonyms: SCARB1, SR-B1, SR-BI, Scavenger Receptor-BI, Scavenger Receptor-B1
Uniprot Accession: P97943, Q61009, Q8WTV0
Entrez GeneID: 20778, 25073, 949
Gene Symbol: SCARB1
Suggested positive control: mouse liver lysate or protein.
References:
Test: WB, Species: Hm, Reference: Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet. (2013) PLoS One, Vol: 8, 4, e61109, Kasbi Chadli F, Nazih H, Krempf M, Nguyen P, Ouguerram K; Pubmed ID: 23613796