SR-BI Polyclonal Antibody, Invitrogen™

SR-BI Antibody, PA1-16803, from Invitrogen™. Species Reactivity: Hamster, Human, Mink, Mouse, Rat, Rodent; Applications: FACS, ICC, IF, IHC (Paraffin), WB.

Brand:  Invitrogen PA116803

Product Code. 11585383

Description

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
Host Species: Goat
Cross Reactivity: Hamster, Human, Mink, Mouse, Rat, Rodent
Isotype: IgG
Immunogen: Synthetic peptide corresponding to the C-terminal residues 400-509 of mouse SR-BI.
Formulation: 100μL purified antibody (3mg/mL) in tris citrate and 0.09% sodium azide; pH 7-8
Synonyms: SCARB1, SR-B1, SR-BI, Scavenger Receptor-BI, Scavenger Receptor-B1
Uniprot Accession: P97943, Q61009, Q8WTV0
Entrez GeneID: 20778, 25073, 949
Gene Symbol: SCARB1
Suggested positive control: mouse liver lysate or protein.
References:
Test: WB, Species: Hm, Reference: Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet. (2013) PLoS One, Vol: 8, 4, e61109, Kasbi Chadli F, Nazih H, Krempf M, Nguyen P, Ouguerram K; Pubmed ID: 23613796

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Specifications

• Antigen: SR-BI
• Conjugate: Unlabeled
• Gene Accession No.: P97943, Q61009, Q8WTV0
• Gene Alias: SCARB1, SR-B1, SR-BI, Scavenger Receptor-BI, Scavenger Receptor-B1
• Host Species: Goat
• Isotype: IgG
• Storage Requirements: Store at 4° C
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Rodent

• Applications: Western Blot
• Formulation: 100μL purified antibody (3mg/mL) in tris citrate and 0.09% sodium azide; pH 7-8
• Format: Purified
• Gene Symbols: SCARB1
• Immunogen: Synthetic peptide corresponding to the C-terminal residues 400-509 of mouse SR-BI.
• Quantity: 100μL
• Primary or Secondary: Primary
• Gene ID (Entrez): 20778, 25073, 949