SPP1 Monoclonal Antibody, Clone: 7C5H12, Invitrogen™
SPP1 Antibody (7C5H12), MA5-17180, from Invitrogen™. Species Reactivity: Human; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.
Brand: Invitrogen MA517180
Code : NEW
Additional Details : Weight : 0.01000kg
DescriptionThe protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human
Immunogen: Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.
Formulation: 100 ug purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide
Uniprot Accession: P10451
Entrez GeneID: 6696
Gene Symbol: SPP1
MA5-17180 targets SPP1 in ICC, IHC, IF and WB applications and shows reactivity with Human samples. The MA5-17180 immunogen is purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli. MA5-17180 detects SPP1 which has a predicted molecular weight of approximately 35.4kDa.
Test: ICC, Dilution: 1:500, Species: Rb, Reference: Restoration of critical-size defects in the rabbit mandible using porous nanohydroxyapatite-polyamide scaffolds. (Jun 2012) Tissue Eng Part A, Vol: 18, 11-12, 1239-52, Guo J,Meng Z,Chen G,Xie D,Chen Y,Wang H,Tang W,Liu L,Jing W,Long J,Guo W,Tian W; Pubmed ID: 22320360
|100μg purified antibody (1mg/mL) in PBS with 0.5% proprietary stabilizer and 0.05% sodium azide|
|avoiding freeze/thaw cycles.|
|Purified recombinant fragment of human SPP1 (amino acids: 167-314) expressed in E. Coli.|