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PON1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA528997

Code : PN

Additional Details : Weight : 0.01000kg

Product Code. 13453117

  • £301.00 / 100µL

Estimated Shipment
22-12-2020

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Description

Description

The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson′s disease.
Specifications

Specifications

PON1
Polyclonal
Unconjugated
PON1
Liquid
PON1
Recombit fragment corresponding to a region within amino acids 1 and 355 of Human PON1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
P27169, P52430
ESA, MVCD5, PON, A-esterase 1, K-45, PON 1, aromatic esterase 1, arylesterase B-type, esterase A, paraoxonase B-type, serum aryldiakylphosphatase, serum aryldialkylphosphatase 1, serum paraoxonase/arylesterase 1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
18979, 5444
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SDS
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