Phospho-THRB (Ser142) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA539818

Product Code. 15596681

Description

Thyroid hormone receptors (TRs) are ligand dependent members of the steroid/retinoic acid superfamily of transcription factors. The two genes encoding TRs identified to date, TR alpha and TR beta, have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half site binding motifs in the orientation of palindromes, direct repeats, or inverted palindromes. The affinities of binding are both variable and influenced differentially by 3,5,3′-triiodo-L-thyronine (T-3).

Specifications

• Antigen: Phospho-THRB (Ser142)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: THRB
• Gene Alias: TR-B1C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2, nuclear receptor subfamily 1 group A member 2, oncogene ERBA2, thyroid hormone nuclear receptor beta variant 1, thyroid hormone receptor beta, thyroid hormone receptor, beta erythroblastic leukemia viral v-erb-a oncogene homolog 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21834, 24831, 7068
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P10828, P37242, P18113
• Gene Symbols: THRB
• Immunogen: A synthetic phosphopeptide derived from human TR-beta 1 around the phosphorylation site of Ser142 (H-P-SP-Y-S)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG