Phospho-POLR2A (Ser1619) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538091

Product Code. 15525021

Description

RPB1 is a subunit of RNA polymerase II which catalyses transcription of RNA from DNA. RPB1 forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template.

Specifications

• Antigen: Phospho-POLR2A (Ser1619)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: POLR2A
• Gene Alias: RPO2; RPOL2,POLR2 ALPHA-AMANITIN RESISTANCE,POLYMERASE II, RNA, SUBUNIT A,RNA POLYMERASE II, 220-KD SUBUNIT,RNA POLYMERASE II, LARGE SUBUNIT,RPB1, S. CEREVISIAE, HOMOLOG OF polymerase (RNA) II (DNA directed) polypeptide A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20020, 363633, 5430
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P24928, P08775
• Gene Symbols: POLR2A
• Immunogen: A synthetic phosphopeptide derived from human POLR2A around the phosphorylation site of Ser1619 (P-T-SP-P-S)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG