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Phospho-GluR4 (Ser862) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538495
Code : NEW
Additional Details : Weight : 0.00900kg
Description
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.Specifications
Phospho-GluR4 (Ser862) | |
Polyclonal | |
Unconjugated | |
GRIA4 | |
Glutamate receptor 4, GluR-4, GluR4, AMPA-selective glutamate receptor 4, GluR-D, Glutamate receptor ionotropic, AMPA 4, GluA4, GRIA4, GLUR4 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
14802, 2893 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P48058, Q9Z2W8 | |
GRIA4 | |
A synthetic phosphopeptide derived from human GluR4 around the phosphorylation site of Ser862 (R-L-SP-I-T) | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |