Phospho-Caspase 6 (Ser257) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538241

Product Code. 15505171

Description

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms.

Specifications

• Antigen: Phospho-Caspase 6 (Ser257)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CASP6
• Gene Alias: MCH2, apoptotic protease MCH-2, caspase 6, apoptosis-related cysteine protease, caspase-6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12368, 83584, 839
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P55212, O08738, O35397
• Gene Symbols: CASP6
• Immunogen: A synthetic phosphopeptide derived from human Caspase 6 around the phosphorylation site of Ser257 (K-V-SP-Q-R)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG