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Phospho-CaMKII alpha/beta/delta (Thr305) Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538238

Code : NEW

Additional Details : Weight : 0.00900kg

Product Code. 15575161

  • £301.00 / 100µg

Estimated Shipment date
from Supplier 07-07-2020

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Description

Description

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.
Specifications

Specifications

Phospho-CaMKII alpha/beta/delta (Thr305)
Polyclonal
Unconjugated
CAMK2D
Liquid
CAMK2A, CAMK2B, CAMK2D
A synthetic phosphopeptide derived from human CaMKII around the phosphorylation site of Thr305 (I-L-TP-T-M)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Q13554, Q13557, Q9UQM7, P11798, P28652, Q6PHZ2, P08413, P11275, P15791
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968, CaMK2-a, CaMK2a, CaMK-2a, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit delta, CaMK-II subunit delta, CAMK2D, CAMKD, CaMK2- delta, CaMK2 delta, CaMK-2 delta
Rabbit
IgG
100 μg
-20°C
Primary
108058, 12322, 12323, 24245, 24246, 25400, 815, 816, 817
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