NGAL/LCN2 Monoclonal Antibody, Clone: 14, Invitrogen™
NGAL/LCN2 Antibody (14), ABS 038-14-02, from Invitrogen™. Species Reactivity: Canine, Human, Porcine; Applications: ELISA, Western Blot.
Brand: Invitrogen ABS0381402
Code : NEW
Additional Details : Weight : 0.01000kg
DescriptionNeutrophil gelatinase-associated lipocalin (NGAL; also called lipocalin 2, siderocalin and neutrophil lipocalin) is a member of the lipocalin family of proteins which bind and transport small lipophilic molecules. NGAL is released by activated neutrophils and occurs as 25-kDa glycosylated single protein chain monomers, which form dimers and small amounts of higher oligomers, as well as complexes with matrix metalloproteinase 9 (MMP-9; gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by acute kidney injury.
Host Species: Mouse
Cross Reactivity: Canine, Human, Porcine
Isotype: IgG1, κ
Immunogen: Recombinant human NGAL adsorbed onto aluminum hydroxide gel.
Formulation: 200μL purified antibody (1mg/mL) in 0.1M PBS with 0.5M NaCl and 15mM sodium azide; pH 7.4
Synonyms: Neutrophil gelatinase-associated lipocalin, HNL; p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3
Uniprot Accession: P80188
Entrez GeneID: 100153501, 3934, 491320
Gene Symbol: LCN2
Specificity: ABS 038-14-02 shows some cross-Specificity with NGAL from pig and dog. Reactivity: ABS 038-14-02 binds human NGAL in solution and coated onto a solid phase. ABS 038-14-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibodies HYB 211-01-02, HYB 211-02-02, ABS 038-04-02, ABS 038-15-02 and ABS 038-26-02. Using biotinylated ABS 038-15-02 as a detection antibody, the assay reacts equally with NGAL monomer and homodimer on a mass basis. With biotinylated ABS 038-14-02 detection antibody, the assay is specific for NGAL homodimer and can be used at sample dilutions giving low levels of total NGAL. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/ml
|200μL purified antibody (1mg/mL) in 0.1M PBS with 0.5M NaCl and 15mM sodium azide; pH 7.4|
|Recombinant human NGAL adsorbed onto aluminum hydroxide gel.|
|100153501, 3934, 491320|
|Neutrophil gelatinase-associated lipocalin, HNL; p25, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Lipocalin-2, Oncogene 24p3|
|Store at 4° C|