MSRA Mouse anti-Human, Rat, Clone: 5B5, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen LFMA0084

Product Code. 10430460

Description

A suggested positive control for this product is HepG2 cells.

Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires reducing equivalents from either DTT or a thioredoxin-regenerating system. MsrA plays an essential role in protecting cells against oxidative damage. The substrates of MsrA include calmodulin, HIV protease and a 1-proteinase-inhibitor. Recent studies indicate that there is a connection between MsrA and Alzheimer′s disease in mammals.

Specifications

• Antigen: MSRA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9UJ68, Q923M1
• Gene Symbols: MSRA
• Immunogen: Purified, recombit, human methionine sulfoxide reductase A protein expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation
• Clone: 5B5
• Gene: MSRA
• Gene Alias: cytosolic methionine-S-sulfoxide reductase
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 29447, 4482
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid