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IRP2 Polyclonal Antibody, Invitrogen™

IRP2 Antibody, PA1-16543, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Brand:  Invitrogen PA116543

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11525313

  • £332.00 / 100┬ÁL


Estimated Shipment
02-01-2018
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Description

Description

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: Synthetic peptide corresponding to the N-terminal residues 1-100 of human IRP2 (UniProt P48200).
Formulation: 100μL purified antibody (1mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Uniprot Accession: Q811J3
Entrez GeneID: 64602
Gene Symbol: IREB2
This antibody is predicted to work in human based on 100% sequence homology, however preliminary data shows poor reactivity against human protein. This antibody also has 72% sequence homology with rat. Suggested positive control: 3T3 whole cell lysate.
Specifications

Specifications

IRP2
Unconjugated
Q811J3
Iron-responsive element binding protein 2, IRE-BP 2, Iron regulatory protein 2
Rabbit
IgG
avoiding freeze/thaw cycles.
Polyclonal
Murine
Western Blot
100μL purified antibody (1mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Purified
IREB2
Synthetic peptide corresponding to the N-terminal residues 1-100 of human IRP2 (UniProt P48200).
100μL
Primary
64602
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