IRAK4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA529700

Product Code. 13473937

Description

PA5-29700 targets IRAK4 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-29700 immunogen is recombit fragment corresponding to a region within amino acids 27 and 288 of Human IRAK4. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: IRAK4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9NWZ3
• Gene Symbols: IRAK4
• Immunogen: Recombit fragment corresponding to a region within amino acids 27 and 288 of Human IRAK4
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.76 mg/mL
• Gene: IRAK4
• Gene Alias: IPD1, IRAK-4, NY-REN-64, REN64, renal carcinoma antigen NY-REN-64
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51135
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid