missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CYR61 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA123143
Code : LD
Additional Details : Weight : 0.01000kg
Description
PA1-23143 detects CYR61 in Human, Mouse and Rat samples. PA1-23143 has been successfully used in Western Blot procedures. PA1-23143 immunogen corresponds to Synthetic peptide from CYR61 (Human). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
CYR61 is a secreted, cysteine-rich, heparin-binding protein encoded by a growth factor inducible immediate-early gene. It promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion and appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA A, VEGA C, MMP1, MMP3, TIMP1, uPA, PAI 1 and integrins alpha 3 and alpha 5. Cyr61 mediated gene regulation is dependent on heparin binding. Down-regulates the expression of alpha-1 and alpha 2 subunits of collagen type 1. Promotes cell adhesion and adhesive signaling through integrin alpha 6/beta 1, cell migration through integrin alpha v/beta 5 and cell proliferation through integrin alpha v/beta 3.Specifications
| CYR61 | |
| Polyclonal | |
| Unconjugated | |
| O00622, P18406, Q9ES72 | |
| CYR61 | |
| Synthetic peptide from CYR61 (Human) | |
| 50 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Western Blot | |
| 0.5 mg/mL | |
| CYR61 | |
| CCN1, GIG1, IGFBP10 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 16007, 3491, 83476 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |