anti-IFN gamma Oligoclonal, Thermo Scientific™

IFN gamma Oligoclonal antibody 710150 from Thermo Scientific™ specifically detects IFN gamma in Mouse samples, and it is validated for Western Blot

Overview
Brand: Invitrogen

Manufacturer Part Number: 710152

Oligoclonal Antibody, IFN gamma, Host Rabbit

UNSPSC: 12352203

Code: NEW

Additional Details:
Additional Details: Weight: 0.00450kg



Product Code. 15387214

Quantity Price
1 £ 281.0 / 100µg
EU Stock 1
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Description and Specification

Specification

Antigen IFN gamma
Applications Western Blotting
Clone 18HCLC
Conjugate Unlabeled
Cross Reactivity Rat
Format Purified
Formulation 100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide
Gene Accession No. P01581
Gene Alias IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG
Gene Symbols IFNG
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma
Isotype IgG
Quantity 100μg
Species Reactivity Rat
Storage Requirements Store at 2-8°C for up to 1 month. For long term storage store at -20°C
Primary or Secondary Primary
Monoclonal or Polyclonal Oligoclonal
Gene ID (Entrez) 25712

IFN-gamma is a member of type II interferon family, and is a dimeric protein consisting of two 146 amino acid subunits. It is involved in immunoregulatory and anti-proliferative functions. It is a potent activator of macrophages, induces the production of cytokines, and upregulates the expression of class I and class II MHC antigens. Activation of IFN-gamma takes place through binding of IFN-gamma receptor I and II, and activating the JAK-STAT pathway. IFN-gamma does not show any homology with IFN-alpha or IFN-beta but human IFN-gamma shows about 40% sequence homology with mouse IFN-gamma.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Clone: 18HCLC
Immunogen: Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma
Formulation: 100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide
Synonyms: IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG
Uniprot Accession: P01581
Entrez GeneID: 25712
Gene Symbol: IFNG
ABfinity recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A. ABfinity oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain.