IFN gamma Monoclonal Antibody, Clone: 18HCLC, Invitrogen™
IFN gamma Antibody (18HCLC), ABfinity Rb Oligoclonal, 710152, from Invitrogen™. Species Reactivity: Rt; Applications: WB.
Brand: Invitrogen 710152
Code : NEW
Additional Details : Weight : 0.00450kg
DescriptionIFN-gamma is a member of type II interferon family, and is a dimeric protein consisting of two 146 amino acid subunits. It is involved in immunoregulatory and anti-proliferative functions. It is a potent activator of macrophages, induces the production of cytokines, and upregulates the expression of class I and class II MHC antigens. Activation of IFN-gamma takes place through binding of IFN-gamma receptor I and II, and activating the JAK-STAT pathway. IFN-gamma does not show any homology with IFN-alpha or IFN-beta but human IFN-gamma shows about 40% sequence homology with mouse IFN-gamma.
Host Species: Rabbit
Cross Reactivity: Rat
Immunogen: Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma
Formulation: 100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide
Synonyms: IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG
Uniprot Accession: P01581
Entrez GeneID: 25712
Gene Symbol: IFNG
ABfinity recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A. ABfinity oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain.
|100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide|
|Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma|
|IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG|
|Store at 2-8°C for up to 1 month. For long term storage store at -20°C|