anti-IFN gamma Oligoclonal, Thermo Scientific™

IFN gamma Oligoclonal antibody 710150 from Thermo Scientific™ specifically detects IFN gamma in Mouse samples, and it is validated for Western Blot

Overview
Brand: Invitrogen

Manufacturer Part Number: 710152

Oligoclonal Antibody, IFN gamma, Host Rabbit

UNSPSC: 12352203

Code: NEW

Additional Details:
Additional Details: Weight: 0.00450kg



Product Code. 15387214

Quantity Price
1 £ 281.0 / 100µg
EU Stock 1
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Description and Specification

Specification

Formulation 100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide
Gene Symbols IFNG
Gene ID (Entrez) 25712
Cross Reactivity Rat
Antigen IFN gamma
Storage Requirements Store at 2-8°C for up to 1 month. For long term storage store at -20°C
Immunogen Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma
Isotype IgG
Primary or Secondary Primary
Format Purified
Gene Accession No. P01581
Clone 18HCLC
Host Species Rabbit
Species Reactivity Rat
Conjugate Unlabeled
Gene Alias IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG
Applications Western Blotting
Quantity 100μg
Monoclonal or Polyclonal Oligoclonal

IFN-gamma is a member of type II interferon family, and is a dimeric protein consisting of two 146 amino acid subunits. It is involved in immunoregulatory and anti-proliferative functions. It is a potent activator of macrophages, induces the production of cytokines, and upregulates the expression of class I and class II MHC antigens. Activation of IFN-gamma takes place through binding of IFN-gamma receptor I and II, and activating the JAK-STAT pathway. IFN-gamma does not show any homology with IFN-alpha or IFN-beta but human IFN-gamma shows about 40% sequence homology with mouse IFN-gamma.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Clone: 18HCLC
Immunogen: Recombinant protein corresponding to amino acids 23–156 of rat interferon gamma
Formulation: 100μg purified antibody (0.5mg/mL) in PBS and 0.09% sodium azide
Synonyms: IFN-gamma, boIFNG, interferon gamma, interferon gamma type 2, interferon-gamma, IFNG, IFI, IFG
Uniprot Accession: P01581
Entrez GeneID: 25712
Gene Symbol: IFNG
ABfinity recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A. ABfinity oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain.