HSD17B6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA528926

Product Code. 13433047

Description

PA5-28926 targets HSD17B6 in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-28926 immunogen is recombit fragment corresponding to a region within amino acids 1 and 317 of Human HSD17B6. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.

Specifications

• Antigen: HSD17B6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HSD17B6
• Format: Liquid
• Gene Symbols: HSD17B6
• Immunogen: Recombit fragment corresponding to a region within amino acids 1 and 317 of Human HSD17B6
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.71 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O14756
• Gene Alias: HSE, RODH, SDR9C6, 17-beta-HSD 6, 17-beta-HSD6, 17-beta-hydroxysteroid dehydrogenase type 6, 3(alpha->beta)-hydroxysteroid epimerase, 3(alpha->beta)-hydroxysteroid epimerasel, 3-alpha->beta-HSE, 3-alpha->beta-hydroxysteroid epimerase, 3-hydroxysteroid epimerase, NAD+ -dependent 3 a
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Primary or Secondary: Primary
• Gene ID (Entrez): 8630