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hnRNP K Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA519484

Code : A0

Additional Details : Weight : 0.01000kg

Product Code. 11347453

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Description

Description

This antibody is predicted to react with rabbit, chicken and zebrafish based on sequence homology.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly. This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have been described for this gene, however, not all of them are fully characterized.
Specifications

Specifications

hnRNP K
Polyclonal
Unconjugated
P61978, P61979, P61980
HNRNPK
Synthetic peptide conjugated to KLH derived from within residues 200 - 300 of Human hnRNP K.
50 μg
Primary
Human, Mouse, Rat
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.1 mg/mL
HNRNPK
RP11-575L7.1, CSBP, FLJ41122, HNRPK, TUNP, dC-stretch binding protein; hnRNP K; transformation up-regulated nuclear protein; transformation upregulated nuclear protein
Rabbit
Antigen affinity chromatography
RUO
117282, 15387, 3190
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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