HLA-ABC Mouse anti-Human, NA/LE, Unlabeled, Clone: DX17, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 560187

Product Code. 15859998

Description

The DX17 monoclonal antibody reacts with a monomorphic epitope expressed on all HLA (human leukocyte antigen) class I molecules examined. DX17 immunoprecipitates HLA class I heavy chains (45kDa) and β2-microglobulin (12kDa) from radiolabeled human cell lines. HLA is determined by a complex segment of the short arm of chromosome 6 and there are many human HLAs encoded in this segment. The antigenic agglomerate is called MHC, for major histocompatibility complex. Examples of class I loci are HLA-A, -B, and -C, which are serologically assayed; class II loci, e.g., HLA-D/DR and DC1, are tested by lymphocytotoxic methods.

Host Species: Mouse
Clone: DX17
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Polyclonal Human NK Cell Line

Blocking Assay, Flow Cytometry

Specifications

• Antigen: HLA-ABC
• Classification: Monoclonal
• Concentration: 1.0mg/mL
• Formulation: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.
• Immunogen: Polyclonal Human NK Cell Line
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: DX17
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C