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FOXP3 Alexa Fluor 647 Monoclonal Antibody, Clone: 3G3, Invitrogen™

FOXP3 Antibody, Alexa Fluor 647 conjugate (3G3), MA5-18160, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Flow Cytometry.

Brand:  Invitrogen MA518160

UNSPSC : 12352203

Code : NEW

Additional Details : Weight : 0.01000kg

Product Code. 15377424

  • £330.00 / 100µg


Estimated Shipment
13-07-2017
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Specifications

Description

FoxP3 (Forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.
Host Species: Mouse
Cross Reactivity: Human, Mouse
Isotype: IgG1
Clone: 3G3
Immunogen: Full-length His-tagged recombinant murine FoxP3
Formulation: 100μg purified antibody (0.5mg/mL) in PBS and 15mM sodium azide; pH 7.4
Synonyms: JM2, AIID, DIETER, IPEX, PIDX, XPID, FOXP3delta7, forkhead box protein P3, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin
Uniprot Accession: Q99JB6, Q9BZS1
Entrez GeneID: 20371, 50943
Gene Symbol: FOXP3
This product detects FOXP3 in Human and Mouse samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Full-length His-tagged recombinant murine FoxP3.
Description & Specifications

Specifications

FOXP3
3G3
Purified
Q99JB6, Q9BZS1
FOXP3
Full-length His-tagged recombinant murine FoxP3
100μg
Primary
20371, 50943
Flow Cytometry
Alexa Fluor 647
100μg purified antibody (0.5mg/mL) in PBS and 15mM sodium azide; pH 7.4
JM2, AIID, DIETER, IPEX, PIDX, XPID, FOXP3delta7, forkhead box protein P3, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin
Murine
IgG1
DO NOT FREEZE!
Monoclonal
Murine