anti-FOXP3 Clone: 3G3

FOXP3 Monoclonal antibody MA5-18159 from Thermo Scientific™ specifically detects FOXP3 in Human and Mouse samples, and it is validated for Flow Cytometry

Overview
Brand: Invitrogen

Manufacturer Part Number: MA518160

Monoclonal Antibody,FOXP3,Alexa Fluor 647

UNSPSC: 12352203

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 15377424

Quantity Price
1 £ 330.0 / 100µg
Estimated Shipment date
from Supplier 16-12-2016
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Description and Specification

Specification

Antigen FOXP3
Applications Flow Cytometry
Clone 3G3
Conjugate Alexa Fluor 647
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μg purified antibody (0.5mg/mL) in PBS and 15mM sodium azide; pH 7.4
Gene Accession No. Q99JB6, Q9BZS1
Gene Alias JM2, AIID, DIETER, IPEX, PIDX, XPID, FOXP3delta7, forkhead box protein P3, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin
Gene Symbols FOXP3
Host Species Mouse
Immunogen Full-length His-tagged recombinant murine FoxP3
Isotype IgG1
Quantity 100μg
Species Reactivity Human, Mouse
Storage Requirements DO NOT FREEZE!
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Gene ID (Entrez) 20371, 50943

FoxP3 (Forkhead box protein 3), a highly conserved forkhead/winged-helix transcription factor, plays a crucial role in maintaining immune homeostasis by governing the development and function of regulatory T cells. It is constitutively expressed at high level in CD25+ CD4+ Treg cells and at low level in a CD25- CD4+ Treg cell subset. Defects in gene encoding FoxP3 protein cause the scurfy phenotype in mice, and in human the IPEX syndrome (immune dysfunction, polyendocrinopathy, enteropathy, X-linked syndrome), also known as X-linked autoimmunity-allergic dysregulation (XLAAD) syndrome.
Host Species: Mouse
Cross Reactivity: Human, Mouse
Isotype: IgG1
Clone: 3G3
Immunogen: Full-length His-tagged recombinant murine FoxP3
Formulation: 100μg purified antibody (0.5mg/mL) in PBS and 15mM sodium azide; pH 7.4
Synonyms: JM2, AIID, DIETER, IPEX, PIDX, XPID, FOXP3delta7, forkhead box protein P3, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin
Uniprot Accession: Q99JB6, Q9BZS1
Entrez GeneID: 20371, 50943
Gene Symbol: FOXP3
This product detects FOXP3 in Human and Mouse samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Full-length His-tagged recombinant murine FoxP3.